Pioneering the development
of engineered IgM antibodies

antibody-solo

PRESENTATIONS & PUBLICATIONS

SITC Poster: IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion

SITC 2021 –  The Society for Immunotherapy of Cancer 36th Annual Meeting & Pre-Conference Programs    November 12-14, 2021 Thierry D. Giffon; Melanie Desbois; Dean Ng, Ph.D.; Poonam…

SITC Abstract: IGM-7354 is an anti-PD-L1 IgM antibody and IL-15 cytokine fusion that enhances NK and CD8+ T cell proliferation and tumor cytotoxicity plus potently reverses T cell exhaustion

SITC 2021 –  The Society for Immunotherapy of Cancer 36th Annual Meeting & Pre-Conference Programs    November 12-14, 2021 Thierry D. Giffon; Melanie Desbois; Dean Ng, Ph.D.; Poonam…

Multimeric IgM Antibodies Targeting DR5 are Potent and Rapid Inducers of Tumor Cell Apoptosis In Vitro and In Vivo

PEGS Europe, Barcelona, Spain – November 4, 2021 Angus M. Sinclair, PhD, Vice President, Immuno-oncology Research IGM Biosciences, Inc., 325 E Middlefield Road, Mountain View, CA 94043 Sinclair-et-al-PEGS-EU-2021

Abstract #132: A Phase 1 Dose Escalation Study of IGM-2323, a Novel Anti-CD20 x Anti-CD3 IgM T Cell Engager (TCE) in Patients with Advanced B-Cell Malignancies

The 63rd ASH Annual Meeting and Exposition – December 11-14, 2021

Multimeric Anti-DR5 IgM Agonist Antibody IGM-8444 Is a Potent Inducer of Cancer Cell Apoptosis and Synergizes with Chemotherapy and BCL-2 Inhibitor ABT-199

Published in Molecular Cancer Therapeutics, October 28, 2021  Authors: Beatrice T. Wang, Tasnim Kothambawala, Ling Wang, Thomas J. Matthew, Susan E. Calhoun, Avneesh K. Saini, Maya F. Kotturi,…

In the Media: An IgM antibody platform to tackle SARS-CoV-2 and its variants

Published in Drug Target Review.

Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants

Published in Nature, 03 June 2021 Citation: Ku, Z., Xie, X., Hinton, P.R. et al. Nasal delivery of an IgM offers broad protection from SARS-CoV-2 variants. Nature (2021)…

Pharmacodynamic Assessment of an IgM Antibody Using BRGSF-HIS Mice

Predict Innovation — May 20, 2021

Next-Generation Approaches to COVID-19 Therapeutics: Clinical Challenges and Engineering Solutions

PEGS Boston – May 11-13, 2021 Session: Novel and Alternative Approaches to Developing Covid-19 Therapeutics – May 11, 2021

Engineering the Future: Next Gen Platforms in Oncology

Cancer Progress Virtual – May 4-6, 2021 Keynote Address – May 4, 2021